The last time I mentioned an add-on was ... a long time ago (Assuming that Quick Auctions doesn't count). I usually spend some time writing a small review of the addon but Shadowed has a nice description on WoWInterface and I'll assume he knows his addon better than I do, I'll just steal it.
•Shadowed Unit Frames on WoWInterface

Description
The main focus of SUF is having a simplistic configuration, while maintaining flexibility that the vast majority of users care about, this prevents unnecessary bloat that sacrifices performance. While you aren't going to be able to set that you want the health bar to be exactly 3.14 pixels outside of the health bar, you can change options that you actually care about such as bar height, ordering, frame height and so on. All configuration can be done on multiple units at the same time through the global configuration, meaning if you want to set the height of Player and Target frames to 50, but then you want to set the height of Target's Target and Target's Target of Target to 30 you can easily do that with changing only two options, instead of having to do it four times for each unit.
Should you be one of those people who needs a little bit of extra configuration then do not despair! An advanced configuration option is included that will enable more unit and general settings giving you better control over everything
Slash commands: /shadoweduf (/suf)
Anchoring
For those who are driven crazy because their frames look to be half a pixel off center of your player frames, you can simply anchor the frame to the player frames and solve the hassle of aligning everything. For example, the target frames are anchored to the right of the player frame, and the Target of Target frames are anchored to the top of the player frames (In the screenshots).
If you tried to drag player, all the other frames will follow it in the same anchoring. Each frame can still be manually positioned and put wherever you want, but this gives you a way of easily anchoring everything and keeping frames nice and aligned without having to use a ruler.
Visibility
Entire units and modules can be enabled or disabled based on zone type; for example, say you want to enable party targets while in arenas but not in a raid instance, or maybe you want to see your targets cast bar in arenas but not in raid instances you can easily change the module to only be enabled in arena zone types. You don't have to swap any profiles or do anything manually.
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