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Toughness
Improves your armor by 15% and decreases the duration of snares by 30%. If you're a tank then you'll want this for the increased armor otherwise get Imp Icy Touch and Glacier Rot.
Improved Icy Touch
Makes Icy Touch do 30% more damage and Frost Fever reduces melee/ranged attack speed by six percent. It's a pretty good talent considering that as a Frost DK you'll often be using Icy Touch.
Glacier Rot
Disease enemies will take 10% more damage from Icy Touch, Howling Blast, and Frost Strike. There is little reason for an enemy not to be disease as a Death Knight so this is a pretty good talent.
Icy Reach
Icy Reach will increase the range of your Icy Touch, Chains of Ice and Howling Blsat by 5/10 yards which is a good thing. I highly suggest getting it, although you could skip it. Range is good for chasing or pulling if you don't want the taunt that Death Grip has. Still might want to skip it, you shouldn't need the range.
Black Ice
This will increase your Frost damage by 30%. This is a rather big number and this is needed if you're specing deep into the Frost tree and will be using a lot of Frost abilities in your rotation.
Nerves of Cold Steel
Increases your chance to hit by 3% with one-handed weapons and increases damage done by your offhand by 15%. Well this one is a tough one. You can skip it for most occasions unless to-hit is something you desperately need.
Icy Talons
Whenever someone's melee attack speed is reduced with Improved Icy Touch (and Frost Fever) then this ability will increase your attack speed by 20% for 20 seconds. Haste is generally not that great for a Death Knight but is still a pretty high increase in DPS with a big 20% number.
Lichborne
This is an instant ability with a 3 minute cooldown. It turns you undead (making you immune to Charm, Fear, and Sleep) and gives melee attacks a 25% chance to miss you for 15 seconds. There is little reason at all not to get this because of the low cooldown and high chance attacks will miss you. In PvP this can help turn the tide against a Warlock or Priest while in PvE this can help tremendously with tanking or even soloing. Grab it.
Annihilation
Increases critical strike chance by 3% and will give you a 100% chance that your Obliterate will do damage without consuming a disease. Obliterate is awesome, critical strike is awesome, and not consuming a disease can mean the disease can last longer on the target or your DPS/rotation won't suffer so much if your next disease misses. Another must have ability.
Runic Power Mastery
Increase your maximum Runic Power by 10/20/30. If you're going a split between Blood and Frost and are getting Dancing Rune Weapon then this will synergize well. Otherwise you'll be regening and using Runic Power so much that more Runic Power isn't going to help.
Killing Machine
Whenever you land a critical strike with an auto-attack then this will give you a 50% chance to get a critical strike with Icy Touch, Howling Blast, or Frost Strike. This is a key ability for Frost DPS because at level 80 your auto attacks should be firing off critical strikes very often and giving your Frost abilities an increased chance is simply awesome.
Frigid Dreadplate
Reduce the chance that melee attacks will miss you by 1%. The question when you get to this talent is a very simple one. It's a very, very, very simple one. Are you planning on tanking? If the answer is yes then this talent is worth it. If the answer is no then you may skip it.
